This article may interest you, if when you launch or try to use Entourage 2004 for Mac or Entourage 2008 for Mac, the program hangs/freezes and you see a spinning wheel that rotates indefinitely.
To reolve this issue, Microsoft KB2500153 recommends you try the following troubleshooting steps:
1. Use the Shift key
2. Reset the Entourage preferences
3. Rename the Microsoft User Data folder